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Heart Disease and Periodontitis ?



Question:

The American Heart Association estimates approximately 20 % of the American public (almost 60 millions) suffer from cardiovascular disease, making it the NUMBER ONE cause of deaths in the U.S

Is there a connection between this and the common gum disease ?

When there is an inflammation of the lining on the inside of the heart and its valves it is called endocarditis. If there is enough of bacterias around (in the blood stream) the valves can be infected, especially if they have been affected by an infection before.

We know now that bacterias enter the bloodstream even during tooth- brushing. Even more so if there is an ongoing undiagnosed periodontal disease. You notice that if there is blood when you brush your teeth.

Another type of cardiovascular disease is when the heart blood vessels gradually thicken due to the build-up of fatty proteins. There will be a a bacterial biofilm (plaque) making the vessels norrower which causes the blood to clot. This obstructs normal flro of blood and the heart muscel get less of nutrients and oxygen and thus function poorley.

The bacterias in this blood vessel plaque is made up by bacterias from the mouth (some 20% - 25%) which has made researchers to believe that people with periodontal disease develop coronary artery disease twice as often than those without periodontal disease !!!

So in short; there are many known contributing factors behind heart disease such as much blood cholesterol, years of smoking, insulin dependent diabetes, high blood pressure, overweight, lack of excercise.


Answer:

A link has been proven between between periodontal disease and heart disease, but we do not know if this is causal.

All we can say at the present time is that patients with periodontal disease are more at risk to heart disease. It may well be that periodontal disease and heart disease merely share the same risk factors, or it might just be that the same overactive white blood cells are responsible for both conditions. We just don't know as yet.

What we do know is that the studies have not yet been done which prove that patients who have their gum disease treated will have a reduced risk of heart disease.

"... To further test the association between periodontal disease and PVD [Peripheral Vascular Disease], we repeated the analysis after removing other vascular conditions from the non-PVD group. Table IV shows that removing other vascular conditions from the non-PVD group did not substantially modify the relationship between periodontal disease and PVD after adjusting for other significant risk factors. "COMMENTS "In this prospective study we found that otherwise health men with clinically significant periodontal disease at baseline had an approximate twofold increase in their risk of subsequent development of PVD. This asociation is INDEPENDENT (emphasis mine) of other well-established cardiovascular risk factors. Two other interesting observations were made: SNIP (2) the strength of the association between periodontal disease and PVD is comparable with that of other cardiovascular risk factors such as family history of heart disease."

Mendez et al. "An Association between Periodontal Disease and Peripheral Vascular Disease" The American Journal of Surgery vol 176 August 1998

If you read any scientific litterature you'll find similar statements was made during the 60s. Today we know, and *should* inform our patinets that it's possible that if they have periodontal disease, they may be at risk for cardiovascular disease !!!! If you are a dentist this is an obligation you have obviously and blatantly missed.

For a long time, we've known that bacteria may affect the heart, but now evidence is mounting that suggests people with periodontal disease may be more at risk for heart disease, and have nearly twice the risk of having a fatal heart attack, than patients without periodontal disease.

There are many different possibilities how this works: on is that the periodontal bacteria enter the blood through inflamed gums and cause small blood clots that contribute to clogged arteries. Another possibility is that the inflammation caused by periodontal disease increases plaque build up, which may contribute to swelling of the arteries.

Sure more research is needed to confirm how periodontal bacteria is affecting the heart but our lack of knowledge should not stop us from acting upon what we know.

This may very well be a fact but it was not the issue that I brought up. I am talking about increased risk, not decreased, however logical that it may be if a risk is removed the effect of its presence is decreased

If you didn't followed me in that all you can do is to re-read my post. Then you will see that all I did was to place periodontal disease in a group together with other situations with a systemic effect on the body.

I feel pretty safe in stating that current data leads scientists to believe that periodontal disease is an important risk factor for heart disease, working in concert with other risk factors such as age, smoking, diabetes, hypertension and elevated blood cholesterol.


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